Nummer 1-hits in de Billboard Hot 100 in 1988
Deze hits stonden in 1988 op nummer 1 in de Billboard Hot 100
| Datum | Artiest | Titel |
| 2 januari | George Michael | Faith |
| 9 januari | Whitney Houston | So emotional |
| 16 januari | George Harrison | Got my mind set on you |
| 23 januari | Michael Jackson | The way you make me feel |
| 30 januari | INXS | Need you tonight |
| 6 februari | Tiffany | Could've been |
| 13 februari | Tiffany | Could've been |
| 20 februari | Exposé | Seasons change |
| 27 februari | George Michael | Father figure |
| 5 maart | George Michael | Father figure |
| 12 maart | Rick Astley | Never gonna give you up |
| 19 maart | Rick Astley | Never gonna give you up |
| 26 maart | Michael Jackson | Man in the mirror |
| 2 april | Michael Jackson | Man in the mirror |
| 9 april | Billy Ocean | Get outta my dreams, get into my car |
| 16 april | Billy Ocean | Get outta my dreams, get into my car |
| 23 april | Whitney Houston | Where do broken hearts go |
| 30 april | Whitney Houston | Where do broken hearts go |
| 7 mei | Terence Trent D'Arby | Wishing well |
| 14 mei | Gloria Estefan & Miami Sound Machine | Anything for you |
| 21 mei | Gloria Estefan & Miami Sound Machine | Anything for you |
| 28 mei | George Michael | One more try |
| 4 juni | George Michael | One more try |
| 11 juni | George Michael | One more try |
| 18 juni | Rick Astley | Together forever |
| 25 juni | Debbie Gibson | Foolish beat |
| 2 juli | Michael Jackson | Dirty Diana |
| 9 juli | Cheap Trick | The flame |
| 16 juli | Cheap Trick | The flame |
| 23 juli | Richard Marx | Hold on to the nights |
| 30 juli | Steve Winwood | Roll with it |
| 6 augustus | Steve Winwood | Roll with it |
| 13 augustus | Steve Winwood | Roll with it |
| 20 augustus | Steve Winwood | Roll with it |
| 27 augustus | George Michael | Monkey |
| 3 september | George Michael | Monkey |
| 10 september | Guns N' Roses | Sweet child o' mine |
| 17 september | Guns N' Roses | Sweet child o' mine |
| 24 september | Bobby McFerrin | Don't worry, be happy |
| 1 oktober | Bobby McFerrin | Don't worry, be happy |
| 8 oktober | Def Leppard | Love bites |
| 15 oktober | UB40 | Red red wine |
| 22 oktober | Phil Collins | Groove kind of love |
| 29 oktober | Phil Collins | Groove kind of love |
| 5 november | Beach Boys | Kokomo |
| 12 november | The Escape Club | Wild, wild West |
| 19 november | Bon Jovi | Bad medicine |
| 26 november | Bon Jovi | Bad medicine |
| 3 december | Will To Power | Baby, I love your way / Freebird medley (Free baby) |
| 10 december | Chicago | Look away |
| 17 december | Chicago | Look away |
| 24 december | Poison | Every rose has its thorn |
| 31 december | Poison | Every rose has its thorn |
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